Nicholas Paquette

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Anna Sokolovska, Christine Becker, Wai‐Ki Ip et al. · Nature Immunology · 2013 · 201 citations · Full text

Serine/threonine acetylation of TGFβ-activated kinase (TAK1) by <i>Yersinia pestis</i> YopJ inhibits innate immune signaling

Nicholas Paquette, Joseph Conlon, C. Sweet et al. · Proceedings of the National Academy of Sciences · 2012 · 180 citations · Full text

Two roles for the<i>Drosophila</i>IKK complex in the activation of Relish and the induction of antimicrobial peptide genes

Deniz Ertürk-Hasdemir, Meike Broemer, François Leulier et al. · Proceedings of the National Academy of Sciences · 2009 · 168 citations · Full text

Molecular Regulation, Innate Immune System, Molecular Biology +20

Caspase-Mediated Cleavage, IAP Binding, and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling

Nicholas Paquette, Meike Broemer, Kamna Aggarwal et al. · Molecular Cell · 2010 · 165 citations · Full text

Transcriptional Regulation, Caspase-mediated Cleavage, Signal Transduction +15

Rudra Interrupts Receptor Signaling Complexes to Negatively Regulate the IMD Pathway

Kamna Aggarwal, Florentina Rus, Christie Vriesema-Magnuson et al. · PLoS Pathogens · 2008 · 112 citations · Full text

Microbial Pathogens, Molecular Regulation, Innate Immune System +23