Christine Becker

Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1β in type 2 diabetes

Seth L. Masters, Aisling Dunne, Shoba Subramanian et al. · Nature Immunology · 2010 · 1.3K citations · Full text

Life Sciences, Endocrinology, Immunology +14

CD36 coordinates NLRP3 inflammasome activation by facilitating intracellular nucleation of soluble ligands into particulate ligands in sterile inflammation

Frederick J. Sheedy, Alena Grebe, Katey J. Rayner et al. · Nature Immunology · 2013 · 906 citations · Full text

Life Sciences, Cell Biology, Immunology +13

TRIF Licenses Caspase-11-Dependent NLRP3 Inflammasome Activation by Gram-Negative Bacteria

Vijay Rathinam, Sivapriya Kailasan Vanaja, Lisa Waggoner et al. · Cell · 2012 · 722 citations · Full text

Life Sciences, Immunology, Microbiology +14

Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense

Kara G. Lassen, Petric Kuballa, Kara L. Conway et al. · Proceedings of the National Academy of Sciences · 2014 · 366 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Activation of caspase-1 by the NLRP3 inflammasome regulates the NADPH oxidase NOX2 to control phagosome function

Anna Sokolovska, Christine Becker, Wai‐Ki Ip et al. · Nature Immunology · 2013 · 205 citations · Full text

Life Sciences, Immunology, Molecular Biology +16