The voltage dependence of NADPH oxidase reveals why phagocytes need proton channels

Thomas E. DeCoursey, Deri Morgan, Vladimir V. Cherny

Nature

Cell PhysiologyMolecular PhysiologySignal TransductionBiochemistryProton Channels +13

HVCN1 modulates BCR signal strength via regulation of BCR-dependent generation of reactive oxygen species

Melania Capasso, Mandeep K. Bhamrah, Tom Henley, +14

Nature Immunology

Signal TransductionBcr-dependent GenerationHeme HomeostasisCell SignalingMedicine +8

Aspartate 112 is the selectivity filter of the human voltage-gated proton channel

Boris Musset, Susan M. Smith, Sindhu Rajan, +3

Nature

Nuclear PhysicsBiochemistryAspartate 112Natural SciencesPhysiology +4

Voltage-gated proton channels maintain pH in human neutrophils during phagocytosis

Deri Morgan, Melania Capasso, Boris Musset, +3

Proceedings of the National Academy of Sciences

InflammationMolecular PhysiologyBiochemistryProfound AcidificationGranulocyte +13

Voltage-gated proton channel in a dinoflagellate

Susan M. Smith, Deri Morgan, Boris Musset, +4

Proceedings of the National Academy of Sciences

Zinc inhibition of monomeric and dimeric proton channels suggests cooperative gating

Boris Musset, Susan M. Smith, Sindhu Rajan, +4

The Journal of Physiology

Synaptic TransmissionProton-coupled Electron TransferMolecular BiologyNeurotransmissionChemical Biology +17

The pH dependence of NADPH oxidase in human eosinophils

Deri Morgan, Vladimir V. Cherny, Ricardo Murphy, +2

The Journal of Physiology

InflammationOxysterolAllergyBiochemistryNadph Oxidase +12

Enhanced activation of an amino-terminally truncated isoform of the voltage-gated proton channel HVCN1 enriched in malignant B cells

Elayne Hondares, Mark Brown, Boris Musset, +10

Proceedings of the National Academy of Sciences

The Antibacterial Activity of Human Neutrophils and Eosinophils Requires Proton Channels but Not BK Channels

Jon Femling, Vladimir V. Cherny, Deri Morgan, +9

The Journal of General Physiology

Detailed comparison of expressed and native voltage‐gated proton channel currents

Boris Musset, Vladimir V. Cherny, Deri Morgan, +4

The Journal of Physiology

EngineeringProton ChannelsNeurotransmissionCellular PhysiologyHyperpolarization (Biology) +15