Moh Tadayyon

8-(3-(<i>R</i>)-Aminopiperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydropurine-2,6-dione (BI 1356), a Highly Potent, Selective, Long-Acting, and Orally Bioavailable DPP-4 Inhibitor for the Treatment of Type 2 Diabetes

Matthias Eckhardt, Elke Langkopf, Michael Mark et al. · Journal of Medicinal Chemistry · 2007 · 281 citations · Full text

Pharmaceutical Science, Xanthine Scaffold, Pharmacotherapy +17

(R)-8-(3-Amino-piperidin-1-yl)-7-but-2-ynyl-3-methyl-1-(4-methyl-quinazolin-2-ylmethyl)-3,7-dihydro-purine-2,6-dione (BI 1356), a Novel Xanthine-Based Dipeptidyl Peptidase 4 Inhibitor, Has a Superior Potency and Longer Duration of Action Compared with Other Dipeptidyl Peptidase-4 Inhibitors

Leo Thomas, Matthias Eckhardt, Elke Langkopf et al. · Journal of Pharmacology and Experimental Therapeutics · 2008 · 277 citations

Inhibition of fatty acid synthase prevents preadipocyte differentiation

Hans Bernhard Schmid, Jörg F. Rippmann, Moh Tadayyon et al. · Biochemical and Biophysical Research Communications · 2005 · 136 citations

Metabolic Syndrome, Metabolism, Medicine +2

Mono‐unsaturated fatty acids protect against β‐cell apoptosis induced by saturated fatty acids, serum withdrawal or cytokine exposure

Hannah J. Welters, Moh Tadayyon, J. H. B. Scarpello et al. · FEBS Letters · 2004 · 103 citations

Immunology, Cell Death, Oxidative Stress +17

Differential protective effects of palmitoleic acid and cAMP on caspase activation and cell viability in pancreatic β-cells exposed to palmitate

Hannah J. Welters, Eleftheria Diakogiannaki, J. Mark Mordue et al. · APOPTOSIS · 2006 · 59 citations

Differential Protective Effects, Palmitoleic Acid, Signal Transduction +11