The Transcriptional Profile of Mesenchymal Stem Cell Populations in Primary Osteoporosis Is Distinct and Shows Overexpression of Osteogenic Inhibitors

Peggy Benisch, Tatjana Schilling, Ludger Klein‐Hitpaß, +10

PLoS ONE

SclerostinBone RepairOsteogenesisStem Cell BiologyOsteoporosis +22

Effects of high glucose on mesenchymal stem cell proliferation and differentiation

Yuming Li, Tatjana Schilling, Peggy Benisch, +9

Biochemical and Biophysical Research Communications

Regenerative MedicineDevelopmental BiologyHigh GlucoseMedicineDiabetes +7

Selenium Supplementation Restores the Antioxidative Capacity and Prevents Cell Damage in Bone Marrow Stromal Cells In Vitro

Regina Ebert, Matthias Ulmer, Sabine Zeck, +6

Stem Cells

Lipid PeroxidationImmunologyRoutine Cell CultureReactive Oxygen SpeciesRedox Biology +16

Pulse treatment with zoledronic acid causes sustained commitment of bone marrow derived mesenchymal stem cells for osteogenic differentiation

Regina Ebert, Sabine Zeck, Ralf Krug, +5

Bone

Regenerative MedicineMesenchymal Stem CellsMedicinePulse TreatmentBone Marrow +6

1,25-Dihydroxyvitamin D3 Treatment Delays Cellular Aging in Human Mesenchymal Stem Cells while Maintaining Their Multipotent Capacity

Barbara Klotz, Birgit Mentrup, Martina Regensburger, +7

PLoS ONE

Basic Osteoporosis TreatmentAdult Stem CellCell DeathLineage CommitmentBiomedical Engineering +19

Acute phase serum amyloid A induces proinflammatory cytokines and mineralization via toll-like receptor 4 in mesenchymal stem cells

Regina Ebert, Peggy Benisch, Melanie Krug, +6

Stem Cell Research

Compound heterozygosity of two functional null mutations in the ALPL gene associated with deleterious neurological outcome in an infant with hypophosphatasia

Christine Hofmann, Johannes G. Liese, Tobias Schwarz, +10

Bone

Developmental AnomalyMendelian DisorderGenetic DisorderAlpl GeneGenetics +7

Krüppel-like factors KLF2 and 6 and Ki-67 are direct targets of zoledronic acid in MCF-7 cells

Regina Ebert, Sabine Zeck, Jutta Meißner-Weigl, +7

Bone

Zoledronic AcidSignal TransductionSignaling PathwayBiochemistryCell Regulation +11

Probenecid as a sensitizer of bisphosphonate-mediated effects in breast cancer cells

Regina Ebert, Jutta Meißner-Weigl, Sabine Zeck, +8

Molecular Cancer

Contact of myeloma cells induces a characteristic transcriptome signature in skeletal precursor cells –Implications for myeloma bone disease

Julia Dotterweich, Katrin Schlegelmilch, Alexander Keller, +7

Bone

Physical InteractionBone Morphogenic ProteinMyeloma CellsBone HomeostasisStem Cells +16