An integrated encyclopedia of DNA elements in the human genome

Ian Dunham, Anshul Kundaje, Shelley Force Aldred, +440

The Journal of the American Medical Association (JAMA) Network (American Medical Association)

ChIP-seq guidelines and practices of the ENCODE and modENCODE consortia

Stephen G. Landt, Georgi K. Marinov, Anshul Kundaje, +44

Genome Research

Histone ModificationsEngineeringElectronic Design AutomationGeneticsComputer Architecture +24

Architecture of the human regulatory network derived from ENCODE data

Mark Gerstein, Anshul Kundaje, Manoj Hariharan, +52

Nature

Dynamic DNA methylation across diverse human cell lines and tissues

Katherine E. Varley, Jason Gertz, Kevin M. Bowling, +10

Genome Research

Epigenetic ChangeGeneticsDna MethylationDna AnalysisMolecular Biology +14

Widespread plasticity in CTCF occupancy linked to DNA methylation

Hao Wang, Matthew T. Maurano, Hongzhu Qu, +11

Genome Research

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyVariable Ctcf Binding +17

MYC Drives Progression of Small Cell Lung Cancer to a Variant Neuroendocrine Subtype with Vulnerability to Aurora Kinase Inhibition

Gürkan Mollaoglu, Matthew R. Guthrie, Stefanie Böhm, +26

Cancer Cell

Variant Neuroendocrine SubtypeAurora Kinase InhibitionOncogenic AgentMedicineBronchial Neoplasm +7

From single-cell to cell-pool transcriptomes: Stochasticity in gene expression and RNA splicing

Georgi K. Marinov, Brian A. Williams, Ken McCue, +4

Genome Research

MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

Abbie S. Ireland, Alexi M. Micinski, David W. Kastner, +18

Cancer Cell

Neuroendocrine FateOncogenic AgentMedicineCancer BiologyCell Biology +5

Distinct Properties of Cell-Type-Specific and Shared Transcription Factor Binding Sites

Jason Gertz, Daniel Savic, Katherine E. Varley, +7

Molecular Cell

ChromatinTranscriptional RegulationSystems BiologyDistinct PropertiesGene Expression +7

A human breast cancer-derived xenograft and organoid platform for drug discovery and precision oncology

Katrin P. Guillen, Maihi Fujita, Andrew Butterfield, +38

Nature Cancer