Rüdiger Hardeland

The changing biological roles of melatonin during evolution: from an antioxidant to signals of darkness, sexual selection and fitness

Dun‐Xian Tan, Rüdiger Hardeland, Lucien C. Manchester et al. · Biological reviews/Biological reviews of the Cambridge Philosophical Society · 2009 · 351 citations

Fitness, Cryptochrome, Sexual Selection +23

Anti-inflammatory actions of melatonin and its metabolites, N1-acetyl-N2-formyl-5-methoxykynuramine (AFMK) and N1-acetyl-5-methoxykynuramine (AMK), in macrophages

Juan C. Mayo, Rosa M. Sáinz, Dun‐Xian Tan et al. · Journal of Neuroimmunology · 2005 · 328 citations

Inflammation, Medicinal Chemistry, Anti-inflammatory +8

Reduced oxidative damage in ALS by high‐dose enteral melatonin treatment

Jochen H. Weishaupt, Claudia Bartels, Esther Pölking et al. · Journal of Pineal Research · 2006 · 286 citations

On the primary functions of melatonin in evolution: Mediation of photoperiodic signals in a unicell, photooxidation, and scavenging of free radicals*

Rüdiger Hardeland, Ivonne Balzer, Burkhard Pöeggeler et al. · Journal of Pineal Research · 1995 · 270 citations

Melatonin, a potent agent in antioxidative defense: Actions as a natural food constituent, gastrointestinal factor, drug and prodrug

Rüdiger Hardeland, Seithikurippu R. Pandi‐Perumal · Nutrition & Metabolism · 2005 · 264 citations · Full text