Rapid lymphatic efflux limits cerebrospinal fluid flow to the brain

Qiaoli Ma, Miriam Ries, Yann Decker, +6

Acta Neuropathologica

Long-term treatment with Ginkgo biloba extract EGb 761 improves symptoms and pathology in a transgenic mouse model of Alzheimer’s disease

Xu Liu, Wenlin Hao, Yiren Qin, +7

Brain Behavior and Immunity

Neurodegenerative DiseasesAlzheimer's DiseaseMedicineLong-term TreatmentDegenerative Pathology +9

Clearance of cerebrospinal fluid from the sacral spine through lymphatic vessels

Qiaoli Ma, Yann Decker, Andreas Müller, +2

The Journal of Experimental Medicine

SurgeryCsf TracersEpendymaCerebrospinal FluidLymphatic System +17

Decreased pH in the aging brain and Alzheimer's disease

Yann Decker, Eszter Németh, Robert Schomburg, +5

Neurobiology of Aging

Alzheimer's DiseaseAgingDementiaVascular DementiaNeurology +3

Lymphatic outflow of cerebrospinal fluid is reduced in glioma

Qiaoli Ma, Felix Schlegel, Samia B. Bachmann, +6

Scientific Reports

Stimulation of TLR4 Attenuates Alzheimer’s Disease–Related Symptoms and Pathology in Tau-Transgenic Mice

Yiren Qin, Yang Liu, Wenlin Hao, +5

The Journal of Immunology

Lipoxin A₄ inhibits IL-1β-induced IL-8 and ICAM-1 expression in 1321N1 human astrocytoma cells

Yann Decker, Gethin J. McBean, Catherine Godson

American Journal of Physiology-Cell Physiology

Normal brain aging and Alzheimer's disease are associated with lower cerebral pH: an in vivo histidine 1H-MR spectroscopy study

Epameinondas Lyros, Andreas Ragoschke-Schumm, Panagiotis Kostopoulos, +8

Neurobiology of Aging

Alzheimer's DiseaseHealth SciencesDementiaPhysiologyLower Cerebral Ph +9

Magnetic resonance imaging of cerebrospinal fluid outflow after low-rate lateral ventricle infusion in mice

Yann Decker, Jonas Krämer, Xin Li, +4

JCI Insight

Brain CirculationBrain LesionCerebrospinal Fluid OutflowMagnetic Resonance ImagingBlood Flow +18

IKKβ Deficiency in Myeloid Cells Ameliorates Alzheimer's Disease-Related Symptoms and Pathology

Yang Liu, Xu Liu, Wenlin Hao, +6

Journal of Neuroscience

ImmunologyImmune RegulationCell DeathInnate ImmunityImmune System +22