Ruthenium-Catalyzed Selective α,β-Deuteration of Bioactive Amines

Lorenz Neubert, Dirk Michalik, Sebastian Bähn, +6

Journal of the American Chemical Society

Bioorganic ChemistryEngineeringNatural SciencesDeuterium IncorporationBorrowing Hydrogen Methodology +8

Pd‐ and Pt‐catalyzed H/D exchange methods and their application for internal MS standard preparation from a Sanofi‐Aventis perspective

Jens Atzrodt, Volker Derdau

Journal of Labelled Compounds and Radiopharmaceuticals

Materials ScienceCatalyst Activation PrinciplesChemical EngineeringEngineeringHeterogeneous Catalysis +8

Highly Selective Directed Iridium‐Catalyzed Hydrogen Isotope Exchange Reactions of Aliphatic Amides

Mégane Valero, Remo Weck, Stefan Güssregen, +2

Angewandte Chemie International Edition

Hydrogen–Deuterium Exchange Reactions of Aromatic Compounds and Heterocycles by NaBD₄‐Activated Rhodium, Platinum and Palladium Catalysts

Volker Derdau, Jens Atzrodt, Jochen Zimmermann, +2

Chemistry - A European Journal

Hydrogen–deuterium Exchange ReactionsEngineeringAromatic CompoundsOrganic ChemistryPalladium Catalysts +14

Iridium-catalysed ortho-H/D and -H/T exchange under basic conditions: C–H activation of unprotected tetrazoles

William J. Kerr, David M. Lindsay, Marc Reid, +4

Chemical Communications

Inorganic ChemistryChemical EngineeringNovel OrganocatalystsEngineeringUnprotected 2-Aryltetrazoles +11

Iridium-Catalyzed Csp³–H Activation for Mild and Selective Hydrogen Isotope Exchange

William J. Kerr, Richard J. Mudd, Marc Reid, +2

ACS Catalysis

Novel OrganocatalystsEngineeringSp3 C–h BondsBiochemistryHydrogen Transition +10

Expanded applicability of iridium(I) NHC/phosphine catalysts in hydrogen isotope exchange processes with pharmaceutically-relevant heterocycles

Jens Atzrodt, Volker Derdau, William J. Kerr, +3

Tetrahedron

Chemical EngineeringPharmaceutically-relevant HeterocyclesEngineeringHydrogen Isotope ExchangeHeterogeneous Catalysis +6

NHC‐Stabilized Iridium Nanoparticles as Catalysts in Hydrogen Isotope Exchange Reactions of Anilines

Mégane Valero, Donia Bouzouita, Alberto Palazzolo, +7

Angewandte Chemie International Edition

Hydrogen Isotope Exchange with Iridium(I) Complexes Supported by Phosphine‐Imidazolin‐2‐imine P,N Ligands

Kristof Jess, Volker Derdau, Remo Weck, +4

Advanced Synthesis & Catalysis

Inorganic ChemistryR PEngineeringBiochemistryIridium Complexes +11

Cabazitaxel is more active than first-generation taxanes in ABCB1(+) cell lines due to its reduced affinity for P-glycoprotein

George E. Durán, Volker Derdau, Dietmar Weitz, +7

Cancer Chemotherapy and Pharmacology

Chemical BiologyBiochemistryNatural SciencesMolecular BiologyCell Lines +5