Takashi Kurohara

N+-C-H···O Hydrogen bonds in protein-ligand complexes

Yukihiro Itoh, Yusuke Nakashima, Shuichiro Tsukamoto et al. · Scientific Reports · 2019 · 140 citations · Full text

Life Sciences, Chemistry, Medicinal Chemistry +17

Identification of Diketopiperazine-Containing 2-Anilinobenzamides as Potent Sirtuin 2 (SIRT2)-Selective Inhibitors Targeting the “Selectivity Pocket”, Substrate-Binding Site, and NAD⁺-Binding Site

Paolo Mellini, Yukihiro Itoh, Elghareeb E. Elboray et al. · Journal of Medicinal Chemistry · 2019 · 27 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +14

Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders

Tetsuya Iida, Yukihiro Itoh, Yukari Takahashi et al. · ChemMedChem · 2021 · 25 citations

Pharmacy, Medicinal Chemistry, Oncology +13

Development of Rapid and Facile Solid‐Phase Synthesis of PROTACs via a Variety of Binding Styles

Hanqiao Xu, Takashi Kurohara, Reina Takano et al. · ChemistryOpen · 2022 · 25 citations · Full text

Pharmacy, Medicinal Chemistry, Molecular Biology +10

Synthesis of β-Allylbutenolides via One-Pot Copper-Catalyzed Hydroallylation/Cyclization of γ-Hydroxybutynoate Derivatives

Yoshihiko Yamamoto, Shinya Shibano, Takashi Kurohara et al. · The Journal of Organic Chemistry · 2014 · 23 citations

Natural Sciences, Chemistry, Medicinal Chemistry +7