Pharmacologic or Genetic Targeting of Glutamine Synthetase Skews Macrophages toward an M1-like Phenotype and Inhibits Tumor Metastasis

Erika M. Palmieri, Alessio Menga, Rosa Martín‐Pérez, +10

Cell Reports

ATP-citrate lyase is essential for macrophage inflammatory response

Vittoria Infantino, Vito Iacobazzi, Ferdinando Palmieri, +1

Biochemical and Biophysical Research Communications

InflammationImmunologyChronic InflammationCell BiologyMacrophage Inflammatory Response +5

A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation

Vittoria Infantino, Vito Iacobazzi, Alessio Menga, +2

Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms

InflammationCytokineIfnγ-triggered InflammationMitochondrial Citrate CarrierMitochondrial Function +10

Acetylation of human mitochondrial citrate carrier modulates mitochondrial citrate/malate exchange activity to sustain NADPH production during macrophage activation

Erika M. Palmieri, Iolanda Spera, Alessio Menga, +7

Biochimica et Biophysica Acta (BBA) - Bioenergetics

MitophagySignal TransductionBiochemistryMitochondrial FunctionCell Signaling +9

Blockade of Glutamine Synthetase Enhances Inflammatory Response in Microglial Cells

Erika M. Palmieri, Alessio Menga, Aurore Lebrun, +4

Antioxidants and Redox Signaling

Elements in support of the ‘non-identity’ of the PGRMC1 protein with the σ2 receptor

Carmen Abate, Mauro Niso, Vittoria Infantino, +2

European Journal of Pharmacology

Protein FunctionMolecular PhysiologySignal TransductionPgrmc1 ProteinMolecular Regulation +10

Iron supplementation is sufficient to rescue skeletal muscle mass and function in cancer cachexia

Elisabeth Wyart, Myriam Y. Hsu, Roberta Sartori, +17

EMBO Reports

NutritionCancer CachexiaIron MetabolismMedicinePhysiology +10

Glufosinate constrains synchronous and metachronous metastasis by promoting anti‐tumor macrophages

Alessio Menga, Marina Serra, Simona Todisco, +11

EMBO Molecular Medicine

SLC25A10 biallelic mutations in intractable epileptic encephalopathy with complex I deficiency

Giuseppe Punzi, Vito Porcelli, Matteo Ruggiu, +20

Human Molecular Genetics

Neurological DisorderGeneticsMolecular BiologyMolecular GeneticsDisease Gene Identification +18

<i><scp>SLC</scp>25A26</i> overexpression impairs cell function via mt<scp>DNA</scp> hypermethylation and rewiring of methyl metabolism

Alessio Menga, Erika M. Palmieri, Antonia Cianciulli, +6

FEBS Journal

Epigenetic ChangeGeneticsDna MethylationMolecular BiologyGene Promoter Hypermethylation +24