Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions

Ralf Bartenschlager, L Ahlborn-Laake, Jan Mous, +1

Journal of Virology

Virus StructureViral ReplicationBiochemistryHepatitis C VirusNatural Sciences +13

Kinetic and structural analyses of hepatitis C virus polyprotein processing

Ralf Bartenschlager, L Ahlborn-Laake, Jan Mous, +1

Journal of Virology

Viral ReplicationAmino AcidsImmunologyMolecular BiologyViral Structural Protein +17

Transcript imaging of the development of human T helper cells using oligonucleotide arrays

Lars Rogge, Elisabetta Bianchi, Mauro Biffi, +11

Nature Genetics

Human CellDevelopmental BiologyOligonucleotide ArraysT-regulatory CellTranscriptomics Technology +5

Identification of amino acid residues critical for endonuclease and integration activities of HIV-1 IN protein in Vitro

Meera Drelich, Roland C. Wilhelm, Jan Mous

Virology

Viral ReplicationBiochemistryAmino AcidProtein FoldingMedicine +9

Characterization of human immunodeficiency virus type 1 mutantswith decreased sensitivity to proteinase inhibitor Ro 31-8959

Helmut Jacobsen, Kaya Yasargil, Dean L. Winslow, +4

Virology

Viral ReplicationHuman RetrovirusPathogenesisImmunologyAntiviral Response +8

Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol

Kerstin Otte, Harald Kranz, Ingo Kober, +15

Molecular and Cellular Biology

In Vivo Resistance to a Human Immunodeficiency Virus Type 1 Proteinase Inhibitor: Mutations, Kinetics, and Frequencies

Helmut Jacobsen, Markus Hänggi, Michael Ott, +5

The Journal of Infectious Diseases

Presenilins Are Processed by Caspase-type Proteases

Hansruedi Loetscher, Ulrich Deuschle, Manfred Brockhaus, +6

Journal of Biological Chemistry

Processing protease and reverse transcriptase from human immunodeficiency virus type I polyprotein in Escherichia coli

Jan Mous, Edgar P. Heimer, S F Le Grice

Journal of Virology

Viral ReplicationPol Precursor PolyproteinProtein ExpressionMedicineNatural Sciences +12

HIV-1 RT-associated ribonuclease H displays both endonuclease and 3′----5′ exonuclease activity.

Octavian Schatz, Jan Mous, S F Le Grice

The EMBO Journal

Viral ReplicationBiochemistryExonuclease ActivityNatural SciencesHuman Retrovirus +9