Kristopher K. Frese

Inhibition of Hedgehog Signaling Enhances Delivery of Chemotherapy in a Mouse Model of Pancreatic Cancer

Kenneth P. Olive, Michael A. Jacobetz, Christian J. Davidson et al. · Science · 2009 · 3.1K citations · Full text

Tumor Biology, Oncology, Pancreatic Cancer +12

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gina M. DeNicola, Florian A. Karreth, Timothy J. Humpton et al. · Nature · 2011 · 2.2K citations · Full text

Oncogenic Agent, Oncogene-induced Nrf2 Transcription, Reactive Oxygen Specie +5

CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer

Kristopher K. Frese, Tashinga E. Bapiro, Tomoaki Nakagawa et al. · Proceedings of the National Academy of Sciences · 2013 · 237 citations · Full text

Tumor Biology, Pancreatic Cancer, Medicine +14

A biobank of small cell lung cancer CDX models elucidates inter- and intratumoral phenotypic heterogeneity

Kathryn Simpson, Ruth Stoney, Kristopher K. Frese et al. · Nature Cancer · 2020 · 161 citations

Intratumoral Phenotypic Heterogeneity, Tumor Heterogeneity, Medicine +10

The Combination of the PARP Inhibitor Olaparib and the WEE1 Inhibitor AZD1775 as a New Therapeutic Option for Small Cell Lung Cancer

Alice Lallo, Kristopher K. Frese, Christopher J. Morrow et al. · Clinical Cancer Research · 2018 · 155 citations · Full text