Michał Romański

Pharmacokinetics of treosulfan and its active monoepoxide in pediatric patients after intravenous infusion of high-dose treosulfan prior to HSCT

Franciszek K. Główka, Anna Kasprzyk, Michał Romański et al. · European Journal of Pharmaceutical Sciences · 2014 · 37 citations

Pharmacology, Pediatric Patients, Toxicology +5

HPLC method for determination of biologically active epoxy-transformers of treosulfan in human plasma: Pharmacokinetic application

Franciszek K. Główka, Michał Romański, Artur Tężyk et al. · Journal of Pharmaceutical and Biomedical Analysis · 2011 · 23 citations

Hplc Method, Pharmaceutical Science, Biochemistry +9

Activation of Prodrug Treosulfan at pH 7.4 and 37°C Accompanied by Hydrolysis of Its Active Epoxides: Kinetic Studies with Clinical Relevance

Michał Romański, Bartosz Urbaniak, Zenon J. Kokot et al. · Journal of Pharmaceutical Sciences · 2015 · 23 citations

Medicinal Chemistry, Pharmaceutical Science, Oxysterol +8

Determination of partition coefficients n-octanol/water for treosulfan and its epoxy-transformers: An example of a negative correlation between lipophilicity of unionized compounds and their retention in reversed-phase chromatography

Franciszek K. Główka, Michał Romański, Anna Siemiątkowska · Journal of Chromatography B · 2013 · 18 citations

Chemical Measurement, Engineering, Biochemistry +11

Kinetic and Mechanistic Study of the pH-Dependent Activation (Epoxidation) of Prodrug Treosulfan Including the Reaction Inhibition in a Borate Buffer

Michał Romański, Whitney Ratajczak, Franciszek K. Główka · Journal of Pharmaceutical Sciences · 2017 · 16 citations

Biochemistry, Medicine, Biocatalysis +7