HPLC method for determination of biologically active epoxy-transformers of treosulfan in human plasma: Pharmacokinetic application

Treosulfan and fludarabine: a new toxicity-reduced conditioning regimen for allogeneic hematopoietic stem cell transplantation

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Medicine, Hematology, Oncology +13

Comparison of blood concentrations of 1,3-butadiene and butadiene epoxides in mice and rats exposed to 1,3-butadiene by inhalation

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Pharmacy, Toxicology, Environmental Toxicology +6

DNA alkylation and interstrand cross-linking by treosulfan

John A. Hartley, C. Caroline O’Hare, Joachim Baumgart · British Journal of Cancer · 1998 · 118 citations · Full text

Medicine, Cancer Biology, Molecular Biology +12

Clinical phase I dose escalation and pharmacokinetic study of high-dose chemotherapy with treosulfan and autologous peripheral blood stem cell transplantation in patients with advanced malignancies.

M. E. Scheulen, Ralf A. Hilger, C. Oberhoff et al. · PubMed · 2000 · 110 citations

Pharmacy, Oncology, Pharmacokinetics +16

Disposition of butadiene monoepoxide and butadiene diepoxide in various tissues of rats and mice following a low-level inhalation exposure to 1,3-butadiene

Janice R. Thornton‐Manning, Alan R. Dahl, William E. Bechtold et al. · Carcinogenesis · 1995 · 108 citations

Pharmacy, Toxicology, Carcinogenesis +16