Enhanced oxidative phosphorylation in NKT cells is essential for their survival and function

Ajay Kumar, Kalyani Pyaram, Emily L. Yarosz, +4

Proceedings of the National Academy of Sciences

DEL-1 restrains osteoclastogenesis and inhibits inflammatory bone loss in nonhuman primates

Jieun Shin, Tomoki Maekawa, Toshiharu Abe, +6

Science Translational Medicine

ATRX loss in glioma results in dysregulation of cell-cycle phase transition and ATM inhibitor radio-sensitization

Tingting Qin, Brendan Mullan, Ramya Ravindran, +24

Cell Reports

Atrx-deficient Gbm CellsCell CycleHigh-grade GliomasGliomaTumor Biology +14

Mammalian Target of Rapamycin Complex 2 Regulates Invariant NKT Cell Development and Function Independent of Promyelocytic Leukemia Zinc-Finger

Nicolas Prevot, Kalyani Pyaram, Evan Bischoff, +3

The Journal of Immunology

Expression and Function of the Homeostatic Molecule Del-1 in Endothelial Cells and the Periodontal Tissue

Jieun Shin, Kavita B. Hosur, Kalyani Pyaram, +4

Clinical and Developmental Immunology

Homeostatic Molecule Del-1Endothelial CellsImmune RegulationImmunologyCell Death +22

Identification of Hot Spots in the Variola Virus Complement Inhibitor (SPICE) for Human Complement Regulation

Viveka Nand Yadav, Kalyani Pyaram, Jayati Mullick, +1

Journal of Virology

Diagnostic VirologyComplement SystemMolecular VirologyPathogenesisViral Pathogenesis +11

Reactive Oxygen Species Regulate the Inflammatory Function of NKT Cells through Promyelocytic Leukemia Zinc Finger

Yeung‐Hyen Kim, Ajay Kumar, Cheong‐Hee Chang, +1

The Journal of Immunology

Keap1-Nrf2 System Plays an Important Role in Invariant Natural Killer T Cell Development and Homeostasis

Kalyani Pyaram, Ajay Kumar, Yeung‐Hyen Kim, +4

Cell Reports

Thymic NF-κB-inducing kinase regulates CD4+ T cell-elicited liver injury and fibrosis in mice

Hong Shen, Liang Sheng, Yi Xiong, +7

Journal of Hepatology

InflammationFibrosisImmune Cell DevelopmentLiver PhysiologyImmunology +13

Influence of Electrostatics on the Complement Regulatory Functions of Kaposica, the Complement Inhibitor of Kaposi’s Sarcoma-Associated Herpesvirus

Kalyani Pyaram, Chris A. Kieslich, Viveka Nand Yadav, +2

The Journal of Immunology