David J. Unett

A Role for β-Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucose-Dependent Insulin Release

Zhi‐Liang Chu, Robert M. Jones, Hongmei He et al. · Endocrinology · 2007 · 292 citations

Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119

Graeme Semple, Beatriz Fioravanti, Imelda Calderon et al. · Journal of Medicinal Chemistry · 2008 · 141 citations · Full text

N-Oleoyldopamine Enhances Glucose Homeostasis through the Activation of GPR119

Zhi‐Liang Chu, Christopher J. Carroll, Ruoping Chen et al. · Molecular Endocrinology · 2009 · 121 citations · Full text

Metabolic Syndrome, Glucose Tolerance, Lipid Synthesis +14

Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor

Daniel J. Buzard, Sun Hee Kim, Luis Lopez et al. · ACS Medicinal Chemistry Letters · 2014 · 70 citations · Full text

Immunology, Potent Functional Antagonist, Inflammation +20

Angiotensin (1–7) does not interact directly with MAS1, but can potently antagonize signaling from the AT1 receptor

Ibragim Gaidarov, John W. Adams, John Frazer et al. · Cellular Signalling · 2018 · 56 citations

Inflammation, Molecular Pharmacology, At1 Receptor +9