Mutational Spectrum, Copy Number Changes, and Outcome: Results of a Sequencing Study of Patients With Newly Diagnosed Myeloma

Brian A. Walker, Eileen M. Boyle, Christopher P. Wardell, +24

Journal of Clinical Oncology

Intraclonal heterogeneity is a critical early event in the development of myeloma and precedes the development of clinical symptoms

Brian A. Walker, Christopher P. Wardell, Lorenzo Melchor, +15

Leukemia

Hematological MalignancyClinical SymptomsMixed-phenotype Acute LeukemiaMalignant Blood DisorderHematology +8

Global methylation analysis identifies prognostically important epigenetically inactivated tumor suppressor genes in multiple myeloma

Martin Kaiser, David C. Johnson, Ping Wu, +7

Blood

Selective FLT3 inhibition of FLT3-ITD+ acute myeloid leukaemia resulting in secondary D835Y mutation: a model for emerging clinical resistance patterns

Andrew S. Moore, Amir Faisal, David González de Castro, +15

Leukemia

Hematological MalignancySecondary D835y MutationEngineeringMixed-phenotype Acute LeukemiaMalignant Blood Disorder +10

Overexpression of EZH2 in multiple myeloma is associated with poor prognosis and dysregulation of cell cycle control

Charlotte Pawlyn, Michael D. Bright, Amy Buros, +13

Blood Cancer Journal

Improved risk stratification in myeloma using a micro<scp>RNA</scp>‐based classifier

Ping Wu, Luca Agnelli, Brian A. Walker, +11

British Journal of Haematology

HSF1 Is Essential for Myeloma Cell Survival and A Promising Therapeutic Target

Jacqueline H. L. Fok, Somaieh Hedayat, Lei Zhang, +14

Clinical Cancer Research

MMSET is the key molecular target in t(4;14) myeloma

Fabio Mirabella, Pingping Wu, Christopher P. Wardell, +4

Blood Cancer Journal

Hematological MalignancyMmset LocusMmset Genetic MapMedicineMalignant Blood Disorder +10

Genetic correlation between multiple myeloma and chronic lymphocytic leukaemia provides evidence for shared aetiology

Molly Went, Amit Sud, Helen E. Speedy, +52

Blood Cancer Journal

Multiple myeloma risk variant at 7p15.3 creates an IRF4-binding site and interferes with CDCA7L expression

Ni Li, David C. Johnson, Niels Weinhold, +9

Nature Communications