Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma

Kewen Hu, Kun Li, Jing Lv, +12

Journal of Clinical Investigation

Chemoprevention StrategySynthetic LethalityCancer BiologyTumor BiologyKras-mutant Lung Adenocarcinoma +14

PGE2 activates EP4 in subchondral bone osteoclasts to regulate osteoarthritis

Wenhao Jiang, Yunyun Jin, Shiwei Zhang, +12

Bone Research

Reprogramming immunosuppressive myeloid cells facilitates immunotherapy for colorectal cancer

Weiqiang Lü, Weiwei Yu, Jiacheng He, +18

EMBO Molecular Medicine

Suppression of KRas-mutant cancer through the combined inhibition of KRAS with PLK1 and ROCK

Jieqiong Wang, Kewen Hu, Jiawei Guo, +7

Nature Communications

Echinacea purpurea polysaccharide prepared by fractional precipitation prevents alcoholic liver injury in mice by protecting the intestinal barrier and regulating liver-related pathways

Wenhao Jiang, Hongkang Zhu, Wenqian Xu, +5

International Journal of Biological Macromolecules

Echinacea Purpurea PolysaccharideHepatologyBiochemistryMedicineLiver Physiology +8

Anti-fatigue effect of<i>Lepidium meyenii</i>Walp. (Maca) on preventing mitochondria-mediated muscle damage and oxidative stress<i>in vivo</i>and<i>vitro</i>

Hongkang Zhu, Wenqian Xu, Ning Wang, +7

Food & Function

Dietary supplementation of <i>Bacillus cereus</i> as probiotics in Pengze crucian carp ( <i>Carassius auratus</i> var. Pengze): Effects on growth performance, fillet quality, serum biochemical parameters and intestinal histology

Gang Yang, Hongzhong Cao, Wenhao Jiang, +7

Aquaculture Research

PrebioticsNutritionProbioticAcid PhosphataseAnimal Nutrition +12

In-depth investigation of the mechanisms of Echinacea purpurea polysaccharide mitigating alcoholic liver injury in mice via gut microbiota informatics and liver metabolomics

Wenhao Jiang, Hongkang Zhu, Chang Liu, +4

International Journal of Biological Macromolecules

Liver MetabolomicsHepatologyBiochemistryMedicineNatural Sciences +13

Ameliorative effects of chlorogenic acid on alcoholic liver injury in mice via gut microbiota informatics

Hongkang Zhu, Wenhao Jiang, Chang Liu, +5

European Journal of Pharmacology

DysbiosisBiochemistryMedicineLiver PhysiologyHepatotoxicity +13

PIWIL2 interacting with IKK to regulate autophagy and apoptosis in esophageal squamous cell carcinoma

Xu Zhao, Lian Huang, Yilu Lu, +6

Cell Death and Differentiation