Graham A. Showell - Concepedia

Author

Graham A. Showell

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

G A Showell, G. A. SHOWELL, G. A. Showell, G.A. Showell, Graham A Showell, Graham A. Showell, Graham Showell, Showell, G.A.

Publications

1.7K

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)University of Würzburg MSD (UK) Limited (United Kingdom)

About

Graham A. Showell is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in drug discovery, pharmacology, and medicine.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	12	13	513
2	Natural Sciences	11	11	447
3	Biochemistry	9	9	301
4	Engineering	1	1	36
5	Chemical Biology	1	1	28

Graham A. Showell

Publications

863

Citations

H-Index

Page 1

	Year	Citations
Synthesis and biological activity of 1,2,4-oxadiazole derivatives: highly potent and efficacious agonists for cortical muscarinic receptors L. J. STREET, R. BAKER, T. BOOK, Journal of Medicinal Chemistry	1990	132
Sila-venlafaxine, a Sila-Analogue of the Serotonin/Noradrenaline Reuptake Inhibitor Venlafaxine: Synthesis, Crystal Structure Analysis, and Pharmacological Characterization J.O. Daiss, Christian Burschka, John Mills, Organometallics Pharmaceutical SciencePharmacological CharacterizationPsychotropic MedicationOrganic ChemistryPharmacotherapy	2006	89
Trimethylsilylpyrazoles as novel inhibitors of p38 MAP kinase: A new use of silicon bioisosteres in medicinal chemistry Richard Conroy, David J. Miller, John Mills, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryPharmaceutical ScienceP38 Map KinaseBiochemistrySilicon Bioisosteres	2006	65
Tetrahydropyridyloxadiazoles: semi-rigid muscarinic ligands Graham A. Showell, T. L. Gibbons, Clare O. Kneen, Journal of Medicinal Chemistry PharmacotherapyChemistryHeterocycle ChemistryPharmaceutical ChemistryMedicinal Chemistry	1991	64
Synthesis, Crystal Structure Analysis, and Pharmacological Characterization of Disila-bexarotene, a Disila-Analogue of the RXR-Selective Retinoid Agonist Bexarotene J.O. Daiss, Christian Burschka, John Mills, Organometallics Medicinal ChemistryPharmacological CharacterizationCrystal Structure AnalysisTwofold Sila-substitutionOphthalmology	2005	61
(R)-Sila-venlafaxine: A selective noradrenaline reuptake inhibitor for the treatment of emesis Graham A. Showell, Matthew J. Barnes, J.O. Daiss, Bioorganic & Medicinal Chemistry Letters Molecular PharmacologyMedicineNeuropharmacologyPharmacotherapyPharmacology	2006	56
Thyroid hormone analogs. Synthesis of 3'-substituted 3,5-diiodo-L-thyronines and quantitative structure-activity studies of in vitro and in vivo thyromimetic activities in rat liver and heart Paul D. Leeson, David Ellis, J. C. EMMETT, Journal of Medicinal Chemistry	1988	52
Synthesis and antihypertensive activity of 6,7-disubstituted trans-4-amino-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-3-ols John Evans, Charles S. Fake, Thomas C. Hamilton, Journal of Medicinal Chemistry	1984	51
Selective thyromimetics. Cardiac-sparing thyroid hormone analogs containing 3'-arylmethyl substituents Paul D. Leeson, John C. Emmett, Virendra P. Shah, Journal of Medicinal Chemistry	1989	40
Ester bio-isosteres: synthesis of oxadiazolyl-1-azabicyclo[2.2.1]heptanes as muscarinic agonists John Saunders, Angus M. MacLeod, Kevin J. Merchant, Journal of the Chemical Society Chemical Communications Chemical EngineeringA. M. MacleodEngineeringPharmaceutical ChemistryBiochemistry	1988	36

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