Alexander Heim‐Riether

Improving potency and selectivity of a new class of non-Zn-chelating MMP-13 inhibitors

Alexander Heim‐Riether, Steven J. Taylor, Shuang Liang et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 50 citations · Full text

Medicinal Chemistry, Medicine, Non-zn-chelating Mmp-13 Inhibitors +8

Fragment-Based Discovery of Indole Inhibitors of Matrix Metalloproteinase-13

Steven J. Taylor, Asitha Abeywardane, Shuang Liang et al. · Journal of Medicinal Chemistry · 2011 · 45 citations · Full text

Matrix Metalloproteases, Molecular Biology, Indole Inhibitors +16

SAR studies of non-zinc-chelating MMP-13 inhibitors: Improving selectivity and metabolic stability

Donghong A. Gao, Zhaoming Xiong, Alexander Heim‐Riether et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 30 citations · Full text

Medicinal Chemistry, Metabolic Stability, Biochemistry +10

A Novel Method for the Synthesis of Imidazo[5,1-<i>f</i>][1,2,4]triazin-4(3<i>H</i>)-ones

Alexander Heim‐Riether, Jason Healy · The Journal of Organic Chemistry · 2005 · 24 citations

Medicinal Chemistry, Novel Method, Derivatives +15

Exploration of cathepsin S inhibitors characterized by a triazole P1–P2 amide replacement

Neil Moss, Zhaoming Xiong, Mike Burke et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 11 citations · Full text

Biochemistry, Medicine, Natural Sciences +9