Miguel A. Maria‐Solano

Efficient reductive desymmetrization of bulky 1,3-cyclodiketones enabled by structure-guided directed evolution of a carbonyl reductase

Xi Chen, Hongliu Zhang, Miguel A. Maria‐Solano et al. · Nature Catalysis · 2019 · 101 citations

Asymmetric Catalysis, Engineering, Heterocyclic +9

Deciphering the Allosterically Driven Conformational Ensemble in Tryptophan Synthase Evolution

Miguel A. Maria‐Solano, Javier Iglesias‐Fernández, Sílvia Osuna · Journal of the American Chemical Society · 2019 · 90 citations

Big data and artificial intelligence (AI) methodologies for computer-aided drug design (CADD)

Jai Woo Lee, Miguel A. Maria‐Solano, Thi Ngoc Lan Vu et al. · Biochemical Society Transactions · 2022 · 71 citations · Full text

Artificial Intelligence, Pharmaceutical Research, Drug Target +21

<i>In Silico</i> Identification and Experimental Validation of Distal Activity-Enhancing Mutations in Tryptophan Synthase

Miguel A. Maria‐Solano, Thomas Kinateder, Javier Iglesias‐Fernández et al. · ACS Catalysis · 2021 · 64 citations · Full text

Protein Assembly, Experimental Validation, Biomolecular Structure Prediction +16

Time Evolution of the Millisecond Allosteric Activation of Imidazole Glycerol Phosphate Synthase

Carla Calvó‐Tusell, Miguel A. Maria‐Solano, Sílvia Osuna et al. · Journal of the American Chemical Society · 2022 · 54 citations · Full text

Biosynthesis, Cellular Enzymology, Biochemistry +15