Joshua R. Sacher

A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis

Tanja Krainz, Michael M. Gaschler, Chaemin Lim et al. · ACS Central Science · 2016 · 231 citations · Full text

Life Sciences, Cell Biology, Pharmacology +17

Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias

Laura Hinze, Maren Pfirrmann, Salmaan Karim et al. · Cancer Cell · 2019 · 105 citations · Full text

Medicine, Cancer Biology, Oncology +14

Exploiting an Asp-Glu “switch” in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia

Florence F. Wagner, Lina Benajiba, Arthur J. Campbell et al. · Science Translational Medicine · 2018 · 96 citations · Full text

Pharmacy, Medicinal Chemistry, Oncology +17

Mitochondria-targeted ROS scavenger improves post-ischemic recovery of cardiac function and attenuates mitochondrial abnormalities in aged rats

Nelson Escobales, Rebeca E. Nuñez, Sehwan Jang et al. · Journal of Molecular and Cellular Cardiology · 2014 · 87 citations · Full text

Life Sciences, Cardiology, Physiology +17

Inhibitors of Glycogen Synthase Kinase 3 with Exquisite Kinome-Wide Selectivity and Their Functional Effects

Florence F. Wagner, Joshua A. Bishop, Jennifer Gale et al. · ACS Chemical Biology · 2016 · 70 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14