Mélina Girardin

Discovery of MK-1439, an orally bioavailable non-nucleoside reverse transcriptase inhibitor potent against a wide range of resistant mutant HIV viruses

Bernard Côté, Jason D. Burch, Ernest Asante‐Appiah et al. · Bioorganic & Medicinal Chemistry Letters · 2013 · 97 citations

Medicine, Antiviral Drug Development, Antiviral Therapy +11

Convergent Kilogram-Scale Synthesis of Dual Orexin Receptor Antagonist

Mélina Girardin, Stéphane G. Ouellet, Danny Gauvreau et al. · Organic Process Research & Development · 2012 · 77 citations

α-Methylpiperidine Core, Convergent Kilogram-scale Synthesis, Orexin Receptor Antagonist +16

A Robust Kilo-Scale Synthesis of Doravirine

Louis‐Charles Campeau, Qinghao Chen, Danny Gauvreau et al. · Organic Process Research & Development · 2016 · 63 citations

Medicinal Chemistry, Natural Sciences, Medicine +14

Cu-Catalyzed N-Arylation of Oxazolidinones:  An Efficient Synthesis of the κ-Opioid Receptor Agonist CJ-15161

Arun K. Ghosh, Janice E. Sieser, Stéphane Caron et al. · The Journal of Organic Chemistry · 2005 · 42 citations

Synthesis of Highly Functionalized Bicyclo[<i>m</i>.<i>n</i>.1]alkanones via a Cationic Reaction Cascade

Roch M. A. Lavigne, Maxime Riou, Mélina Girardin et al. · Organic Letters · 2005 · 38 citations

Chemical Engineering, Acid-mediated Prins/pinacol, Engineering +13