Rory Curtis

TRPV3 is a calcium-permeable temperature-sensitive cation channel

Haoxing Xu, I. Scott Ramsey, Suhas A. Kotecha et al. · Nature · 2002 · 943 citations

Natural Sciences, Biophysics, Cell Biology +12

Substrate-specific Activation of Sirtuins by Resveratrol

Matt Kaeberlein, Thomas McDonagh, Birgit Heltweg et al. · Journal of Biological Chemistry · 2005 · 742 citations · Full text

Education, Biochemistry, Molecular Biology +15

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

Javier Apfeld, Greg O’Connor, Tom McDonagh et al. · Genes & Development · 2004 · 645 citations · Full text

Life Sciences, Biochemistry, Biology +17

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh et al. · Journal of Medicinal Chemistry · 2005 · 525 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +13

Inhibition of SIRT1 Catalytic Activity Increases p53 Acetylation but Does Not Alter Cell Survival following DNA Damage

Jonathan M. Solomon, Rao Pasupuleti, Lei Xu et al. · Molecular and Cellular Biology · 2005 · 487 citations · Full text

Life Sciences, Molecular Biology, Oncology +17