Concepedia

Javier Apfeld

JA

22

Publications

5K

Citations

18

H-Index

1995

Active since

Affiliations

Harvard University(Current)

Center for Systems Biology

Northeastern University

University of California, San Francisco

Massachusetts Institute of Technology

Javier Apfeld is an author at Harvard University specializing in medicine, developmental biology, and gene expression.

Top concepts

MedicineDevelopmental BiologyCell BiologyCell SignalingGene ExpressionSystems BiologySignal TransductionLongevityBiologyGene Regulation

Publications per year

1995–2022

22

Publications

22

aph-1 and pen-2 Are Required for Notch Pathway Signaling, γ-Secretase Cleavage of βAPP, and Presenilin Protein Accumulation

Ross S. Francis, Garth McGrath, Jianhua Zhang et al. · Developmental Cell · 2002 · 794 citations · Full text

Protein Function, Signal Transduction, γ-Secretase Cleavage +9

Sirt1 Regulates Insulin Secretion by Repressing UCP2 in Pancreatic β Cells

Laura Bordone, Maria Carla Motta, Frédéric Picard et al. · PLoS Biology · 2005 · 702 citations · Full text

Insulin Signaling, Metabolic Syndrome, Signaling Pathway +16

The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in <i>C. elegans</i>

Javier Apfeld, Greg O’Connor, Tom McDonagh et al. · Genes & Development · 2004 · 634 citations · Full text

Regulation of lifespan by sensory perception in Caenorhabditis elegans

Javier Apfeld, Cynthia Kenyon · Nature · 1999 · 567 citations

Biology, Neural Mechanism, Longevity +5

Regulation of Life-Span by Germ-Line Stem Cells in <i>Caenorhabditis elegans</i>

Nuno Arantes-Oliveira, Javier Apfeld, Andrew Dillin et al. · Science · 2002 · 515 citations

Aging, Reproductive Biology, Stem Cell Biology +20

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