Mariël Brok

Imatinib mesylate (STI571) is a substrate for the breast cancer resistance protein (BCRP)/ABCG2 drug pump

Herman Burger, Hans van Tol, Antonius W.M. Boersma et al. · Blood · 2004 · 412 citations · Full text

Large-Scale Genetic Perturbations Reveal Regulatory Networks and an Abundance of Gene-Specific Repressors

Patrick Kemmeren, Katrin Sameith, Loes A. L. van de Pasch et al. · Cell · 2014 · 304 citations · Full text

Systems Biology, Functional Genomics, Engineering +12

The Specificity and Topology of Chromatin Interaction Pathways in Yeast

Tineke L. Lenstra, Joris J. Benschop, Tae Soo Kim et al. · Molecular Cell · 2011 · 247 citations · Full text

Chromatin, Cell Division, Chromatin Remodeling +11

Chronic imatinib mesylate exposure leads to reduced intracellular drug accumulation by induction of the ABCG2 (BCRP) and ABCB1 (MDR1) drug transport pumps

Herman Burger, Hans van Tol, Mariël Brok et al. · Cancer Biology & Therapy · 2005 · 204 citations · Full text

Cancer Research, Oncology, Drug Transport Pumps +15

Functional Overlap and Regulatory Links Shape Genetic Interactions between Signaling Pathways

Sake van Wageningen, Patrick Kemmeren, Philip Lijnzaad et al. · Cell · 2010 · 133 citations · Full text

Signal Transduction, Functional Genomics, Genetics +13