Wendy L. Snelson

Free-Wilson and Structural Approaches to Co-optimizing Human and Rodent Isoform Potency for 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitors

Frederick W. Goldberg, Andrew G. Leach, James S. Scott et al. · Journal of Medicinal Chemistry · 2012 · 38 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +16

A novel series of p38 MAP kinase inhibitors for the potential treatment of rheumatoid arthritis

Dearg S. Brown, Andrew Belfield, George R. Brown et al. · Bioorganic & Medicinal Chemistry Letters · 2004 · 28 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

The discovery of N-cyclopropyl-4-methyl-3-[6-(4-methylpiperazin-1-yl)-4-oxoquinazolin-3(4H)-yl]benzamide (AZD6703), a clinical p38α MAP kinase inhibitor for the treatment of inflammatory diseases

Dearg S. Brown, John G. Cumming, Paul A. Bethel et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 11 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9