Detection of preinvasive cancer cells

Vadim Backman, Michael B. Wallace, Lev T. Perelman, +19

Nature

EngineeringCancer DetectionBiomedical ImagingMolecular ImagingPreinvasive Cancer Cells +6

Withaferin A inhibits breast cancer invasion and metastasis at sub‐cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation

Jose Thaiparambil, Laura Bender, Thota Ganesh, +8

International Journal of Cancer

Both Microtubule-Stabilizing and Microtubule-Destabilizing Drugs Inhibit Hypoxia-Inducible Factor-1α Accumulation and Activity by Disrupting Microtubule Function

Daniel Escuín, Erik R. Kline, Paraskevi Giannakakou

Cancer Research

Chemoprevention StrategyCytoskeletonRedox BiologyTumor AngiogenesisTumor Biology +15

Vimentin regulates lung cancer cell adhesion through a VAV2–Rac1 pathway to control focal adhesion kinase activity

Lauren S. Havel, Erik R. Kline, Alessandra M. Salgueiro, +1

Oncogene

Tumor BiologyVav2–rac1 PathwayMedicineCell AdhesionCell Interaction +9

FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells

LaTonia Taliaferro‐Smith, Elaine M. Oberlick, Tongrui Liu, +11

Oncotarget

LKB1 Represses Focal Adhesion Kinase (FAK) Signaling via a FAK-LKB1 Complex to Regulate FAK Site Maturation and Directional Persistence

Erik R. Kline, John A. Shupe, Melissa Gilbert‐Ross, +2

Journal of Biological Chemistry

Long-Term Exposure to AZT, but not d4T, Increases Endothelial Cell Oxidative Stress and Mitochondrial Dysfunction

Erik R. Kline, Leda Bassit, Brenda I. Hernández-Santiago, +8

Cardiovascular Toxicology

InflammationMitochondrial DysfunctionLipid PeroxidationPhysiologyImmunology +8

Vascular oxidative stress and nitric oxide depletion in HIV-1 transgenic rats are reversed by glutathione restoration

Erik R. Kline, Dean J. Kleinhenz, Bill Liang, +5

American Journal of Physiology-Heart and Circulatory Physiology

Localization‐specific LKB1 loss in head and neck squamous cell carcinoma metastasis

Erik R. Kline, Susan Müller, Lin Pan, +3

Head & Neck

STE20-related Kinase Adaptor Protein α (STRADα) Regulates Cell Polarity and Invasion through PAK1 Signaling in LKB1-null Cells

Carrie M. Eggers, Erik R. Kline, Diansheng Zhong, +2

Journal of Biological Chemistry

Lkb1-null CellsMolecular RegulationCancer Cell PolarityCellular PhysiologyTumor Biology +15