Class D β-Lactamases: Are They All Carbapenemases?

Nuno T. Antunes, Toni L. Lamoureaux, Márta Tóth, +3

Antimicrobial Agents and Chemotherapy

Extended-spectrum β-LactamasesClass DAntibiotic ResistanceBacterial PathogensDrug Resistance +17

Discovery of Antibiotic ( <i>E</i> )-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3 <i>H</i> )-one

Renee A. Bouley, Malika Kumarasiri, Zhihong Peng, +12

Journal of the American Chemical Society

Discovery of a New Class of Non-β-lactam Inhibitors of Penicillin-Binding Proteins with Gram-Positive Antibacterial Activity

Peter I. O’Daniel, Zhihong Peng, Hualiang Pi, +19

Journal of the American Chemical Society

Linezolid-resistant MrsaPenicillin-binding ProteinsAntimicrobial ChemotherapyDrug ResistanceMolecular Pharmacology +20

Structural Basis for Carbapenemase Activity of the OXA-23 β-Lactamase from Acinetobacter baumannii

Clyde A. Smith, Nuno T. Antunes, Nichole K. Stewart, +5

Chemistry & Biology

Antimicrobial Drug DiscoveryBiochemistryBacteriologyStructural BasisOxa-23 β-Lactamase +7

Structure–Activity Relationship for the Oxadiazole Class of Antibiotics

Edward Spink, Derong Ding, Zhihong Peng, +15

Journal of Medicinal Chemistry

Class D β-lactamases do exist in Gram-positive bacteria

Márta Tóth, Nuno T. Antunes, Nichole K. Stewart, +4

Nature Chemical Biology

Gram-negative BacteriologyMedicineBacteriologyClass D β-LactamasesMicrobiology +3

The Class A β-Lactamase FTU-1 Is Native to Francisella tularensis

Nuno T. Antunes, Hilary Frase, Márta Tóth, +1

Antimicrobial Agents and Chemotherapy

BacteriologyAntibiotic ResistanceBacterial PathogensDrug ResistanceFrancisella Tularensis +16

Quorum-sensing regulator sdiA and marA overexpression is involved in in vitro-selected multidrug resistance of Escherichia coli

María M. Tavío, Virginia Aquili, José B. Poveda, +3

Journal of Antimicrobial Chemotherapy

Structural Basis for Enhancement of Carbapenemase Activity in the OXA-51 Family of Class D β-Lactamases

Clyde A. Smith, Nuno T. Antunes, Nichole K. Stewart, +4

ACS Chemical Biology

Enzyme Active SiteAntimicrobial Drug DiscoveryAntimicrobial Resistance GeneHealth SciencesBiochemistry +13

Crystal Structure of Carbapenemase OXA-58 from Acinetobacter baumannii

Clyde A. Smith, Nuno T. Antunes, Márta Tóth, +1

Antimicrobial Agents and Chemotherapy

Crystal StructureAntimicrobial Drug DiscoveryBiochemistryMedicineNatural Sciences +12