Synergistic, collaterally sensitive β-lactam combinations suppress resistance in MRSA

Patrick R. Gonzales, Mitchell W. Pesesky, Renee A. Bouley, +9

Nature Chemical Biology

Antimicrobial Resistance GeneHealth SciencesAntibioticsMedicinePharmacology +6

Structure–Activity Relationship for the 4(3<i>H</i>)-Quinazolinone Antibacterials

Renee A. Bouley, Derong Ding, Zhihong Peng, +8

Journal of Medicinal Chemistry

Discovery of Antibiotic ( <i>E</i> )-3-(3-Carboxyphenyl)-2-(4-cyanostyryl)quinazolin-4(3 <i>H</i> )-one

Renee A. Bouley, Malika Kumarasiri, Zhihong Peng, +12

Journal of the American Chemical Society

Synthesis and Evaluation of 1,2,4-Triazolo[1,5-<i>a</i>]pyrimidines as Antibacterial Agents Against <i>Enterococcus faecium</i>

Huan Wang, Mijoon Lee, Zhihong Peng, +6

Journal of Medicinal Chemistry

Antibacterial AgentsE. FaeciumAntimicrobial ChemotherapyAntibiotic ResistanceDrug Resistance +18

Conformational Dynamics in Penicillin-Binding Protein 2a of Methicillin-Resistant <i>Staphylococcus aureus</i>, Allosteric Communication Network and Enablement of Catalysis

Kiran V. Mahasenan, Rafael Molina, Renee A. Bouley, +5

Journal of the American Chemical Society

Conformational DynamicsProtein AssemblyCross-linking StepsMolecular BiologyAnalytical Ultracentrifugation +15

The Quinazolinone Allosteric Inhibitor of PBP 2a Synergizes with Piperacillin and Tazobactam against Methicillin-Resistant Staphylococcus aureus

Jeshina Janardhanan, Renee A. Bouley, Siseth Martínez‐Caballero, +10

Antimicrobial Agents and Chemotherapy

A Genome-Wide Profiling of Glioma Patients with an IDH1 Mutation Using the Catalogue of Somatic Mutations in Cancer Database

Amrit L. Pappula, Shayaan Rasheed, Golrokh Mirzaei, +2

Cancers

Cancer DatabaseEngineeringGeneticsPathologyDisease Gene Identification +20

Structural Determinants Influencing the Potency and Selectivity of Indazole-Paroxetine Hybrid G Protein–Coupled Receptor Kinase 2 Inhibitors

Renee A. Bouley, Helen V. Waldschmidt, M.C. Cato, +7

Molecular Pharmacology

A New Paroxetine-Based GRK2 Inhibitor Reduces Internalization of the μ-Opioid Receptor

Renee A. Bouley, Zara Y. Weinberg, Helen V. Waldschmidt, +4

Molecular Pharmacology

Structure-Based Design of Selective, Covalent G Protein-Coupled Receptor Kinase 5 Inhibitors

Rachel A. Rowlands, M.C. Cato, Helen V. Waldschmidt, +6

ACS Medicinal Chemistry Letters