Concepedia

Jason Sousa

JS

25

Publications

1.1K

Citations

18

H-Index

2007

Active since

Affiliations

Walter Reed Army Institute of Research(Current)

University of Mississippi

Armed Forces Research Institute of Medical Science

University of Pittsburgh

United States Army Medical Research and Development Command

Jason Sousa is an author at Walter Reed Army Institute of Research specializing in medicine, pharmacology, and drug discovery.

Top concepts

Publications per year

2007–2021

25

Publications

25

The metabolism of primaquine to its active metabolite is dependent on CYP 2D6

Brandon Pybus, Sean R. Marcsisin, Xiannu Jin et al. · Malaria Journal · 2013 · 183 citations · Full text

CYP450 phenotyping and accurate mass identification of metabolites of the 8-aminoquinoline, anti-malarial drug primaquine

Brandon Pybus, Jason Sousa, Xiannu Jin et al. · Malaria Journal · 2012 · 121 citations · Full text

Comparison of MDCK-MDR1 and Caco-2 cell based permeability assays for anti-malarial drug screening and drug investigations

Xiannu Jin, ThuLan Luong, Necole Reese et al. · Journal of Pharmacological and Toxicological Methods · 2014 · 104 citations

, , +10

Tafenoquine and NPC-1161B require CYP 2D metabolism for anti-malarial activity: implications for the 8-aminoquinoline class of anti-malarial compounds

Sean R. Marcsisin, Jason Sousa, Gregory A. Reichard et al. · Malaria Journal · 2014 · 84 citations · Full text

Differential CYP 2D6 Metabolism Alters Primaquine Pharmacokinetics

Brittney Potter, Lisa H. Xie, Chau Vuong et al. · Antimicrobial Agents and Chemotherapy · 2015 · 77 citations · Full text

, , +12

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