Xiaohong Xu

Integrated Profiling of MicroRNAs and mRNAs: MicroRNAs Located on Xq27.3 Associate with Clear Cell Renal Cell Carcinoma

Liang Zhou, Jiahao Chen, Zhizhong Li et al. · PLoS ONE · 2010 · 690 citations · Full text

Medicine, Cancer Biology, Oncology +16

Targeting the TGFβ pathway with galunisertib, a TGFβRI small molecule inhibitor, promotes anti-tumor immunity leading to durable, complete responses, as monotherapy and in combination with checkpoint blockade

Rikke Holmgaard, David Schaer, Yanxia Li et al. · Journal for ImmunoTherapy of Cancer · 2018 · 369 citations · Full text

Life Sciences, Immunology, Oncology +17

Reversal of Phenotypic Abnormalities by CRISPR/Cas9-Mediated Gene Correction in Huntington Disease Patient-Derived Induced Pluripotent Stem Cells

Xiaohong Xu, Yilin Tay, Bernice Sim et al. · Stem Cell Reports · 2017 · 226 citations · Full text

Life Sciences, Genetics, Neuroscience +17

A thiol probe for measuring unfolded protein load and proteostasis in cells

Moore Z. Chen, Nagaraj S. Moily, Jessica L. Bridgford et al. · Nature Communications · 2017 · 193 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Preclinical assessment of galunisertib (LY2157299 monohydrate), a first-in-class transforming growth factor-β receptor type I inhibitor

Jonathan M. Yingling, William T. McMillen, Lei Yan et al. · Oncotarget · 2017 · 173 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +12