The Homeodomain Protein HOXB13 Regulates the Cellular Response to Androgens

John D. Norris, Ching‐yi Chang, Bryan M. Wittmann, +5

Molecular Cell

Signal TransductionDevelopmental BiologyEndocrine MechanismMedicineHormonal Receptor +6

CaM Kinase Kinase β-Mediated Activation of the Growth Regulatory Kinase AMPK Is Required for Androgen-Dependent Migration of Prostate Cancer Cells

Daniel E. Frigo, Matthew K. Howe, Bryan M. Wittmann, +6

Cancer Research

Androgen ReceptorProstate Cancer CellsCell ProliferationTumor BiologyCamkkβ Splice Variant +22

Metabolomic Analysis of Bone Morphogenetic Protein Receptor Type 2 Mutations in Human Pulmonary Endothelium Reveals Widespread Metabolic Reprogramming

Joshua P. Fessel, Rizwan Hamid, Bryan M. Wittmann, +7

Pulmonary Circulation

Bladder Cancer Biomarker Discovery Using Global Metabolomic Profiling of Urine

Bryan M. Wittmann, Steven M. Stirdivant, Matthew Mitchell, +8

PLoS ONE

Prognostic BiomarkersUrologyGenitourinary CancerCohort 2Medicine +13

Definition of Functionally Important Mechanistic Differences among Selective Estrogen Receptor Down-regulators

Bryan M. Wittmann, Andrea B. Sherk, Donald P. McDonnell

Cancer Research

Precision medicine screening using whole-genome sequencing and advanced imaging to identify disease risk in adults

Bradley A. Perkins, C. Thomas Caskey, Pamila Brar, +23

Proceedings of the National Academy of Sciences

Genetic EpidemiologyMultiomicsHigh Throughput SequencingWgs Variant InterpretationBiostatistics +15

The breast cell growth inhibitor, estrogen down regulated gene 1, modulates a novel functional interaction between estrogen receptor alpha and transcriptional elongation factor cyclin T1

Bryan M. Wittmann, Koh Fujinaga, Huayun Deng, +2

Oncogene

Breast OncologySignal TransductionDevelopmental BiologySignaling PathwayNovel Functional Interaction +10

Induction of Krüppel-Like Factor 5 Expression by Androgens Results in Increased CXCR4-Dependent Migration of Prostate Cancer Cells<i>in Vitro</i>

Daniel E. Frigo, Andrea B. Sherk, Bryan M. Wittmann, +6

Molecular Endocrinology

Androgen ReceptorKrüppel-like Factor 5Increased Cxcr4-dependent MigrationCancer BiologyTumor Biology +15

A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

Elias A. El-Habr, Luiz Gustavo Dubois, Fanny Burel‐Vandenbos, +27

Acta Neuropathologica

Neuro-oncologyGaba MetabolismGhb ProductionCell RegulationGlioma +9

Metabolomics analysis reveals distinct profiles of nonmuscle‐invasive and muscle‐invasive bladder cancer

Divya Sahu, Yair Lotan, Bryan M. Wittmann, +2

Cancer Medicine