Young Rock Chung

EZH2 Is Required for Germinal Center Formation and Somatic EZH2 Mutations Promote Lymphoid Transformation

Wendy Béguelin, Relja Popovic, Matt Teater et al. · Cancer Cell · 2013 · 828 citations · Full text

Chromatin, Developmental Biology, Germ Cell +9

ASXL1 Mutations Promote Myeloid Transformation through Loss of PRC2-Mediated Gene Repression

Omar Abdel‐Wahab, Mazhar Adli, Lindsay M. LaFave et al. · Cancer Cell · 2012 · 585 citations · Full text

Hematological Malignancy, Chromatin, Somatic Variant +8

SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition

Eun Hee Kim, Janine O. Ilagan, Yang Liang et al. · Cancer Cell · 2015 · 558 citations · Full text

Genome Instability, Somatic Variant, Genetics +8

Loss of BAP1 function leads to EZH2-dependent transformation

Lindsay M. LaFave, Wendy Béguelin, Richard P. Koche et al. · Nature Medicine · 2015 · 392 citations · Full text

Chromatin, Signal Transduction, Signal Recognition +3

Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins

Stanley Chun-Wei Lee, Heidi Dvinge, Eun Hee Kim et al. · Nature Medicine · 2016 · 352 citations · Full text

Hematological Malignancy, Rna Processing, Systems Biology +7