Estrogen Modulates NFκB Signaling by Enhancing IκBα Levels and Blocking p65 Binding at the Promoters of Inflammatory Genes via Estrogen Receptor-β

Dongqi Xing, Suzanne Oparil, Hao Yu, +5

PLoS ONE

MDM2-Mediated Ubiquitination of Angiotensin-Converting Enzyme 2 Contributes to the Development of Pulmonary Arterial Hypertension

Hui Shen, Jiao Zhang, Chen Wang, +11

Circulation

O-GlcNAc Modification of NFκB p65 Inhibits TNF-α-Induced Inflammatory Mediator Expression in Rat Aortic Smooth Muscle Cells

Dongqi Xing, Kaizheng Gong, Wenguang Feng, +4

PLoS ONE

Triptolide attenuates pressure overload-induced myocardial remodeling in mice via the inhibition of NLRP3 inflammasome expression

Rujun Li, Kuiying Lu, Yao Wang, +6

Biochemical and Biophysical Research Communications

InflammationCardiac MuscleCardiomyopathyHeart FailureCell Signaling +8

Inhibition of transforming growth factor-β signaling induces left ventricular dilation and dysfunction in the pressure-overloaded heart

Jason Lucas, Yun Zhang, Peng Li, +8

American Journal of Physiology-Heart and Circulatory Physiology

Heart FailureVentricular DilationTransgenic Mouse ModelCardiovascular FunctionAngiogenesis +17

A Novel Protein Kinase A-independent, β-Arrestin-1-dependent Signaling Pathway for p38 Mitogen-activated Protein Kinase Activation by β2-Adrenergic Receptors

Kaizheng Gong, Zijian Li, Ming Xu, +3

Journal of Biological Chemistry

Acute<i>O</i>-GlcNAcylation prevents inflammation-induced vascular dysfunction

Rob H. P. Hilgers, Dongqi Xing, Kaizheng Gong, +3

American Journal of Physiology-Heart and Circulatory Physiology

Vascular DiseaseImmunologyCardiovascular PharmacologyPharmacotherapyIncrease Protein O-glcnacylation +14

Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice

Deshan Yao, Liuxiang Bao, Sichuan Wang, +5

Free Radical Biology and Medicine

InflammationMolecular PharmacologyCardiovascular ToxicityMolecular PhysiologyMedicine +10

Hypoxia induces downregulation of PPAR-γ in isolated pulmonary arterial smooth muscle cells and in rat lung via transforming growth factor-β signaling

Kaizheng Gong, Dongqi Xing, Peng Li, +6

American Journal of Physiology-Lung Cellular and Molecular Physiology

Lung InflammationRat LungChronic HypoxiaOxidative StressInflammation +17

The nonspecific anti-inflammatory therapy with methotrexate for patients with chronic heart failure

Kaizheng Gong, Zhengang Zhang, Xiaonin Sun, +5

American Heart Journal

Heart FailureChronic Heart FailureCardiorenal SyndromesCardiovascular DiseaseMedicine +7