Sheng‐Chuan Yang

Discovery of Pyrrole−Indoline-2-ones as Aurora Kinase Inhibitors with a Different Inhibition Profile

Chao‐Cheng Chiang, Yu‐Hsiang Lin, Shu Lin et al. · Journal of Medicinal Chemistry · 2010 · 59 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +15

Discovery of 4-Aryl-<i>N</i>-arylcarbonyl-2-aminothiazoles as Hec1/Nek2 Inhibitors. Part I: Optimization of in Vitro Potencies and Pharmacokinetic Properties

Ying-Shuan E. Lee, Shih‐Hsien Chuang, Lynn Y.L. Huang et al. · Journal of Medicinal Chemistry · 2014 · 39 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Copper(I)-Catalyzed Nitrile-Addition/<i>N</i>-Arylation Ring-Closure Cascade: Synthesis of 5,11-Dihydro-6<i>H</i>-indolo[3,2-<i>c</i>]quinolin-6-ones as Potent Topoisomerase-I Inhibitors

Wen-Yun Hsueh, Ying-Shuan E. Lee, Min-Sian Huang et al. · Journal of Medicinal Chemistry · 2021 · 28 citations · Full text

Pharmacy, Chemistry, Medicinal Chemistry +10

Discovery of T-1101 tosylate as a first-in-class clinical candidate for Hec1/Nek2 inhibition in cancer therapy

Shih‐Hsien Chuang, Ying-Shuan E. Lee, Lynn Y.L. Huang et al. · European Journal of Medicinal Chemistry · 2020 · 20 citations

Medicine, Medicinal Chemistry, Pharmacology +6

Synthesis and structure–activity relationship of 3-O-acylated (–)-epigallocatechins as 5α-reductase inhibitors

Shu Lin, Yu‐Hsiang Lin, Mengju Lin et al. · European Journal of Medicinal Chemistry · 2010 · 18 citations

Pharmacy, Medicinal Chemistry, Pharmacology +13