Philippe Chemla

The mode of action and the structure of a herbicide in complex with its target: binding of activated hydantocidin to the feedback regulation site of adenylosuccinate synthetase.

Raymonde Fonné‐Pfister, Philippe Chemla, E. R. Ward et al. · Proceedings of the National Academy of Sciences · 1996 · 74 citations · Full text

Crystal Structure, Target Enzyme, Aldo-keto Reductase +17

Stereoselective synthesis of (+)-hydantocidin

Philippe Chemla · Tetrahedron Letters · 1993 · 55 citations

Bioorganic Chemistry, Organic Chemistry, Stereoselective Synthesis +2

An Enzyme-Bound Bisubstrate Hybrid Inhibitor of Adenylosuccinate Synthetase

Stephen Hanessian, Pu‐Ping Lu, Jean‐Yves Sancéau et al. · Angewandte Chemie International Edition · 1999 · 39 citations

Medicinal Chemistry, Biosynthesis, Aldo-keto Reductase +12

Synthesis of surrogate structures related to the herbicidal agent hydantocidin

Stephen Hanessian, Jean‐Yves Sancéau, Philippe Chemla · Tetrahedron · 1995 · 38 citations

Medicinal Chemistry, Surrogate Structures, Biochemistry +8

Synthesis and Diastereoselective Reactions of Optically Active Dienone-Iron Tricarbonyl Complexes. Synthesis of Tertiary α-Hydroxyaldehydes and γ-Hydroxycrotonaldehydes as Pure Enantiomers of Known Absolute Configuration

M. FRANCK‐NEUMANN, Philippe Chemla, Daniel Martina · Synlett · 1990 · 33 citations

Asymmetric Catalysis, Enantioselective Synthesis, Engineering +14