Jay K. Mandula

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

Jay K. Mandula, Shiun Chang, Eslam Mohamed et al. · Cancer Cell · 2022 · 130 citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +10

Baseline Serum Inflammatory Proteins Predict Poor CAR T Outcomes in Diffuse Large B-cell Lymphoma

Rawan Faramand, Sae Bom Lee, Michael D. Jain et al. · Blood Cancer Discovery · 2024 · 32 citations · Full text

Spatial and functional targeting of intratumoral Tregs reverses CD8+ T cell exhaustion and promotes cancer immunotherapy

Lei Zhou, Maria Velegraki, Yi Wang et al. · Journal of Clinical Investigation · 2024 · 28 citations · Full text

Jagged2 targeting in lung cancer activates anti-tumor immunity via Notch-induced functional reprogramming of tumor-associated macrophages

Jay K. Mandula, Rosa A. Sierra-Mondragon, Rachel V. Jimenez et al. · Immunity · 2024 · 23 citations · Full text

Tumor-associated Macrophages, Cancer Immunosurveillance, Medicine +12

Proteotoxic stress response drives T cell exhaustion and immune evasion

Yi Wang, Anjun Ma, No Joon Song et al. · Nature · 2025 · 15 citations · Full text