Eslam Mohamed

STING Promotes the Growth of Tumors Characterized by Low Antigenicity via IDO Activation

Henrique Lemos, Eslam Mohamed, Lei Huang et al. · Cancer Research · 2016 · 315 citations · Full text

Immunology, Immunoediting, Pathology +18

The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake

Álvaro de Mingo Pulido, Kay Hänggi, Daiana P. Celias et al. · Immunity · 2021 · 220 citations · Full text

Signal Transduction, Inhibitory Receptor Tim-3, Cgas-sting Pathway +9

The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling

Eslam Mohamed, Rosa A. Sierra, Jimena Trillo-Tinoco et al. · Immunity · 2020 · 210 citations · Full text

Cancer Immunosurveillance, Signal Transduction, Receptor Tyrosine Kinase +6

ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression

Yu Cao, Jimena Trillo-Tinoco, Rosa A. Sierra et al. · Nature Communications · 2019 · 150 citations · Full text

Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responses

Jay K. Mandula, Shiun Chang, Eslam Mohamed et al. · Cancer Cell · 2022 · 130 citations · Full text

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +10