Dysregulation of HSG triggers vascular proliferative disorders

Kuang‐Hueih Chen, Xiaomei Guo, Dalong Ma, +8

Nature Cell Biology

ThrombosisVascular DiseaseAutoimmune DiseaseEndothelial DysfunctionCell Death +4

Mitofusin 2 Triggers Vascular Smooth Muscle Cell Apoptosis via Mitochondrial Death Pathway

Xiaomei Guo, Kuang‐Hueih Chen, Yanhong Guo, +3

Circulation Research

Macrophage–NLRP3 Activation Promotes Right Ventricle Failure in Pulmonary Arterial Hypertension

Ruaa Al‐Qazazi, Patrícia Lima, Sasha Z. Prisco, +14

American Journal of Respiratory and Critical Care Medicine

Mitofusin-2 Is a Major Determinant of Oxidative Stress-mediated Heart Muscle Cell Apoptosis

Tao Shen, Ming Zheng, Chunmei Cao, +6

Journal of Biological Chemistry

Epigenetic Dysregulation of the Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increases Mitotic Mitochondrial Fission and Promotes Pulmonary Arterial Hypertension

Kuang‐Hueih Chen, Asish Dasgupta, Jian-Hui Lin, +13

Circulation

Identification of novel dynamin‐related protein 1 (Drp1) GTPase inhibitors: <i>Therapeutic potential of Drpitor1 and Drpitor1a in cancer and cardiac ischemia‐reperfusion injury</i>

Danchen Wu, Asish Dasgupta, Kuang‐Hueih Chen, +10

The FASEB Journal

Role of mitofusin 2 (Mfn2) in controlling cellular proliferation

Kuang‐Hueih Chen, Asish Dasgupta, Jinhui Ding, +3

The FASEB Journal

MitophagyImmunologyCell ProliferationCancer BiologyCellular Physiology +14

Increased Drp1-Mediated Mitochondrial Fission Promotes Proliferation and Collagen Production by Right Ventricular Fibroblasts in Experimental Pulmonary Arterial Hypertension

Lian Tian, François Potus, Danchen Wu, +5

Frontiers in Physiology

Overexpression of Mitofusin 2 inhibited oxidized low-density lipoprotein induced vascular smooth muscle cell proliferation and reduced atherosclerotic lesion formation in rabbit

Yanhong Guo, Kuang‐Hueih Chen, Wei Gao, +4

Biochemical and Biophysical Research Communications

InflammationVascular DiseaseCardiovascular DiseaseLow-density LipoproteinMedicine +9

Mutation of the protein kinase A phosphorylation site influences the anti-proliferative activity of mitofusin 2

Wei Zhou, Kuang‐Hueih Chen, Wenjing Cao, +4

Atherosclerosis

Anti-proliferative ActivityMitophagyProtein FunctionSignal TransductionCell Division +12