Meghana S. Pagadala

The GPCR–Gαs–PKA signaling axis promotes T cell dysfunction and cancer immunotherapy failure

Victoria H. Wu, Bryan S. Yung, Farhoud Faraji et al. · Nature Immunology · 2023 · 85 citations · Full text

Life Sciences, Immunology, Oncology +12

Osteoclast Activated FoxP3+ CD8+ T-Cells Suppress Bone Resorption in vitro

Zachary S. Buchwald, Jennifer R. Kiesel, Richard J. DiPaolo et al. · PLoS ONE · 2012 · 78 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Domain-swapped T cell receptors improve the safety of TCR gene therapy

Michael T. Bethune, Marvin H. Gee, Mario Bunse et al. · eLife · 2016 · 65 citations · Full text

Life Sciences, Biotechnology, Immunology +17

Germline modifiers of the tumor immune microenvironment implicate drivers of cancer risk and immunotherapy response

Meghana S. Pagadala, Timothy J. Sears, Victoria H. Wu et al. · Nature Communications · 2023 · 64 citations · Full text

Medicine, Immunology, Oncology +17

Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma

Owen Chapman, Jens Luebeck, Sunita Sridhar et al. · Nature Genetics · 2023 · 63 citations · Full text

Medicine, Molecular Biology, Oncology +17