Bryan M. Lewis

Eribulin Binds at Microtubule Ends to a Single Site on Tubulin To Suppress Dynamic Instability

Jennifer Smith, Leslie Wilson, Olga Azarenko et al. · Biochemistry · 2009 · 325 citations · Full text

Medicine, Oncology, Pharmacology +15

Eribulin Induces Irreversible Mitotic Blockade: Implications of Cell-Based Pharmacodynamics for <i>In vivo</i> Efficacy under Intermittent Dosing Conditions

Murray J. Towle, Kathleen A. Salvato, Bruce F. Wels et al. · Cancer Research · 2010 · 142 citations

Medicine, Oncology, Pharmacology +16

Commercial Manufacture of Halaven®: Chemoselective Transformations En Route to Structurally Complex Macrocyclic Ketones

Francis G. Fang, Brian C. Austad, Trevor L. Calkins et al. · Synlett · 2013 · 63 citations

Pharmacy, Chemistry, Medicinal Chemistry +16

Determination of the Relative and Absolute Stereochemistry of Fostriecin (CI-920)

Dale L. Boger, Masataka Hikota, Bryan M. Lewis · The Journal of Organic Chemistry · 1997 · 59 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

Process Development of Halaven®: Synthesis of the C14-C35 Fragment via Iterative Nozaki-Hiyama-Kishi Reaction-Williamson Ether Cyclization

Charles E. Chase, Brian C. Austad, Farid Benayoud et al. · Synlett · 2013 · 45 citations

Natural Sciences, Chemistry, Organic Chemistry +4