Tim Dejaegere

Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

Sara Cipolat, Tomasz Rudka, Dieter Hartmann et al. · Cell · 2006 · 727 citations · Full text

Signal Transduction, Mitochondrial Function, Biochemistry +9

γ-Secretase Heterogeneity in the Aph1 Subunit: Relevance for Alzheimer’s Disease

Lutgarde Serneels, Jérôme Van Biervliet, Katleen Craessaerts et al. · Science · 2009 · 256 citations · Full text

Protein Secretion, Molecular Biology, Neurochemical Biomarkers +19

Differential contribution of the three Aph1 genes to γ-secretase activity <i>in vivo</i>

Lutgarde Serneels, Tim Dejaegere, Katleen Craessaerts et al. · Proceedings of the National Academy of Sciences · 2005 · 180 citations · Full text

Coordinated and widespread expression of γ-secretase in vivo: evidence for size and molecular heterogeneity

Sébastien S. Hébert, Lutgarde Serneels, Tim Dejaegere et al. · Neurobiology of Disease · 2004 · 149 citations · Full text

Molecular Heterogeneity, Protein Secretion, Signal Transduction +12

Deficiency of Aph1B/C-γ-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment

Tim Dejaegere, Lutgarde Serneels, Martin Schäfer et al. · Proceedings of the National Academy of Sciences · 2008 · 84 citations · Full text