Guohui Chuai

DeepCRISPR: optimized CRISPR guide RNA design by deep learning

Guohui Chuai, Hanhui Ma, Jifang Yan et al. · Genome biology · 2018 · 551 citations · Full text

Single Guide Rna, Machine Learning, Engineering +18

Pan-Peptide Meta Learning for T-cell receptor–antigen binding recognition

Yicheng Gao, Yuli Gao, Yuxiao Fan et al. · Nature Machine Intelligence · 2023 · 143 citations · Full text

Immunology, Antigen Processing, T Cell Immunity +2

A deep generative model for multi-view profiling of single-cell RNA-seq and ATAC-seq data

Gaoyang Li, Shaliu Fu, Shuguang Wang et al. · Genome biology · 2022 · 95 citations · Full text

Advances and challenges in deep generative models for de novo molecule generation

Dongyu Xue, Yukang Gong, Zhaoyi Yang et al. · Wiley Interdisciplinary Reviews Computational Molecular Science · 2018 · 86 citations

Engineering, Machine Learning, Deep Generative Models +17

FL-QSAR: a federated learning-based QSAR prototype for collaborative drug discovery

Shaoqi Chen, Dongyu Xue, Guohui Chuai et al. · Bioinformatics · 2020 · 82 citations