Human cytomegalovirus-encoded chemokine receptor US28 promotes tumorigenesis

David Maussang, Dennis Verzijl, Marijke van Walsum, +6

Proceedings of the National Academy of Sciences

Inactive MutantMedicineImmunologyAntiviral ResponseSpread Herpesvirus +8

Enhanced therapeutic efficacy of 5'deoxy-5-fluorouridine in 5-fluorouracil resistant head and neck tumours in relation to 5-fluorouracil metabolising enzymes

BJM Braakhuis, EA de Bruijn, E. Laurensse, +2

British Journal of Cancer

5-Fluorouracil Resistant HeadMedicinePharmacologyPathology5-Fluorouracil Metabolising Enzymes +10

Evidence for a role of the monoclonal antibody E48 defined antigen in cell-cell adhesion in squamous epithelia and head and neck squamous cell carcinoma

A. H. G. J. Schrijvers, Martijn Gerretsen, Jan M. Fritz, +4

Experimental Cell Research

Squamous EpitheliaMedicineImmunologyImmunoeditingPathology +7

Superior localisation and imaging of radiolabelled monoclonal antibody E48 F(ab')2 fragment in xenografts of human squamous cell carcinoma of the head and neck and of the vulva as compared to monoclonal antibody E48 IgG

Martijn Gerretsen, JS Suh, Marijke van Walsum, +3

British Journal of Cancer

Superior LocalisationMedicineAntibody E48 IggPathologyBreast Cancer +7

Radioimmunotherapy of human head and neck squamous cell carcinoma xenografts with 131I-labelled monoclonal antibody E48 IgG

Martijn Gerretsen, AHGJ Schrijvers, Marijke van Walsum, +4

British Journal of Cancer

Radiation TherapyMalignant DiseaseMedicinePathologyHuman Head +6

Preclinical chemotherapy on human head and neck cancer xenografts grown in athymic nude mice

Boudewijn J.M. Braakhuis, Guus A. M. S. Van Dongen, Marian Bagnay, +2

Head & Neck

Construction and characterization of the chimeric monoclonal antibody E48 for therapy of head and neck cancer

Ruud H. Brakenhoff, Frank B. van Gog, James E. Looney, +3

Cancer Immunology Immunotherapy

Neck CancerMedicineImmunologyAntibody ScreeningHead And Neck Cancer +7

Complete ablation of small squamous cell carcinoma xenografts with186Re-labeled monoclonal antibody E48

Martijn Gerretsen, Gerard W.M. Visser, Ruud H. Brakenhoff, +3

Cell Biochemistry and Biophysics

Tumoral PathologyOncologyMedicineCancer Cell BiologyPathology +7

Preclinical antitumor activity of 5-aza-2′-deoxycytidine agains human head and neck cancer xenografts

Boudewijn J.M. Braakhuis, Guus AMS van Dongen, Marijke van Walsum, +2

Investigational New Drugs

Tumor BiologyOncologyMedicineHead And Neck CancerPreclinical Antitumor Activity +6

Antitumor activity of brequinar sodium (Dup-785) against human head and neck squanmous cell carcinoma xenografts

B.J.M. Braakhuis, Guus A.M.S. van Dongen, Godefridus J. Peters, +2

Cancer Letters

Tumor BiologyMedicinal ChemistryAntitumor ActivityOncogenic AgentMedicine +10