Induction of autophagy by spermidine promotes longevity

Tobias Eisenberg, Heide Knauer, Alexandra Schauer, +26

Nature Cell Biology

Lifespan ExtensionCell AutophagyMitophagyLongevityAutophagy +4

Nanomechanical Basis of Selective Gating by the Nuclear Pore Complex

Roderick Y. H. Lim, Birthe Fahrenkrog, Joachim Köser, +3

Science

Flexible phenylalanine-glycine nucleoporins as entropic barriers to nucleocytoplasmic transport

Roderick Y. H. Lim, Ning‐Ping Huang, Joachim Köser, +5

Proceedings of the National Academy of Sciences

Molecular BiologyCytoskeletonCollective BehaviorSingle Molecule BiophysicsMembrane Transport +14

Nuclear mRNA Export Requires Complex Formation between Mex67p and Mtr2p at the Nuclear Pores

Helena Santos-Rosa, Horacio Moreno, George Simos, +4

Molecular and Cellular Biology

Cryo-electron Tomography Provides Novel Insights into Nuclear Pore Architecture: Implications for Nucleocytoplasmic Transport

Daniel Stoffler, Bernhard Feja, Birthe Fahrenkrog, +3

Journal of Molecular Biology

Nuclear StructureMicroscopyNuclear Pore ArchitectureNatural SciencesMolecular Biology +7

The<i>S. cerevisiae</i>HtrA-like protein Nma111p is a nuclear serine protease that mediates yeast apoptosis

Birthe Fahrenkrog, Ursula Sauder, Ueli Aebi

Journal of Cell Science

Protein FunctionYeast ApoptosisNatural SciencesApoptosisCell Death +10

Lamin A/C–dependent Localization of Nesprin-2, a Giant Scaffolder at the Nuclear Envelope

Thorsten Libotte, Hafida Zaim, Sabu Abraham, +11

Molecular Biology of the Cell

Protein AssemblyMolecular BiologyNuclear Envelope LocalizationCytoskeletonCellular Physiology +18

Early Parenteral Nutrition Evokes a Phenotype of Autophagy Deficiency in Liver and Skeletal Muscle of Critically Ill Rabbits

Sarah Derde, Ilse Vanhorebeek, Fabián Güiza, +8

Endocrinology

NutritionAutophagy DeficiencyExperimental NutritionObesityMetabolic Syndrome +17

Domain-specific antibodies reveal multiple-site topology of Nup153 within the nuclear pore complex

Birthe Fahrenkrog, Bohumil Maco, Ammon M. Fager, +4

Journal of Structural Biology

Protein FunctionNuclear StructureProtein AssemblyNatural SciencesMolecular Biology +9

The inhibitor-of-apoptosis protein Bir1p protects against apoptosis in <i>S. cerevisiae</i> and is a substrate for the yeast homologue of Omi/HtrA2

David Walter, Silke Wissing, Frank Madeo, +1

Journal of Cell Science

Metazoan ApoptosisMedicineNatural SciencesApoptosisAutophagy +13