Michael R. Collins

Practical and innate carbon–hydrogen functionalization of heterocycles

Yuta Fujiwara, Janice A. Dixon, Fionn O’Hara et al. · Nature · 2012 · 910 citations · Full text

Organic Chemistry, Organometallic Catalysis, Carbon–hydrogen Functionalization +1

A New Reagent for Direct Difluoromethylation

Yuta Fujiwara, Janice A. Dixon, Rodrigo A. Rodriguez et al. · Journal of the American Chemical Society · 2012 · 612 citations

Medicinal Chemistry, Alkylfluorine Substituents, Engineering +11

Discovery of (10 <i>R</i> )-7-Amino-12-fluoro-2,10,16-trimethyl-15-oxo-10,15,16,17-tetrahydro- <i>2H</i> -8,4-(metheno)pyrazolo[4,3- <i>h</i> ][2,5,11]-benzoxadiazacyclotetradecine-3-carbonitrile (PF-06463922), a Macrocyclic Inhibitor of Anaplastic Lymphoma Kinase (ALK) and c-ros Oncogene 1 (ROS1) with Preclinical Brain Exposure and Broad-Spectrum Potency against ALK-Resistant Mutations

Ted W. Johnson, Paul Richardson, Simon Bailey et al. · Journal of Medicinal Chemistry · 2014 · 571 citations · Full text

Strain-release amination

Ryan Gianatassio, Justin M. Lopchuk, Jie Wang et al. · Science · 2016 · 546 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Bioorganic Chemistry +11

Scalable and safe synthetic organic electroreduction inspired by Li-ion battery chemistry

Byron K. Peters, Kevin X. Rodriguez, Solomon H. Reisberg et al. · Science · 2019 · 467 citations · Full text

Chemical Engineering, Engineering, Battery Electrode Materials +14