Xiaochen Tian

Design, synthesis and biological evaluation of sphingosine-1-phosphate receptor 2 antagonists as potent 5-FU-resistance reversal agents for the treatment of colorectal cancer

Dongdong Luo, Yuhang Zhang, Shuang Yang et al. · European Journal of Medicinal Chemistry · 2021 · 17 citations · Full text

Medicine, Pharmacology, Colorectal Cancer +9

Asymmetric α-Regioselective [3 + 2] Annulation of Morita–Baylis–Hillman Carbonates: Construction of Three Contiguous Stereocenters with Vicinal Quaternary Carbon Centers

Xiaochen Tian, Yongxing Zhang, Hao Dong et al. · The Journal of Organic Chemistry · 2022 · 16 citations

Asymmetric Catalysis, Broad Substrate Scope, Chemical Engineering +14

Catalyst-free and oxidant-free tandem aza-Mannich/cyclization/aromatization of <i>C</i>,<i>N</i>-cyclic azomethine imines with enamides: facile synthesis of 5,6-dihydropyrazolo[5,1-<i>a</i>]isoquinolines

Hao Dong, Yongxing Zhang, Xiaochen Tian et al. · Green Chemistry · 2022 · 14 citations

Engineering, Heterocyclic, Facile Synthesis +8

Synthesis of functionalized 3,2′-pyrrolidinyl spirooxindoles <i>via</i> domino 1,6-addition/annulation reactions of <i>para</i>-quinone methides and 3-chlorooxindoles

Xiaochen Tian, Yongxing Zhang, Weiwu Ren et al. · Organic Chemistry Frontiers · 2021 · 13 citations

Combinatorial Chemistry, Diversity Oriented Synthesis, Engineering +9

Catalytic enantioselective nitrone cycloadditions enabling collective syntheses of indole alkaloids

Xiaochen Tian, Tengfei Xuan, Jing-Kun Gao et al. · Nature Communications · 2024 · 12 citations · Full text