Bryan Pursell

ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading

Paul Mak, Irwin Leav, Bryan Pursell et al. · Cancer Cell · 2010 · 369 citations · Full text

Urology, Genitourinary Cancer, Gleason Grading +7

GLI1 regulates a novel neuropilin‐2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation

Hira Lal Goel, Bryan Pursell, Cheng Chang et al. · EMBO Molecular Medicine · 2013 · 161 citations · Full text

Signal Transduction, Signaling Pathway, Medicine +12

A laminin 511 matrix is regulated by TAZ and functions as the ligand for the α6Bβ1 integrin to sustain breast cancer stem cells

Cheng Chang, Hira Lal Goel, Huijie Gao et al. · Genes & Development · 2015 · 150 citations · Full text

Cancer Biology, Mammary Gland Development, Tumor Biology +18

Regulated Splicing of the α6 Integrin Cytoplasmic Domain Determines the Fate of Breast Cancer Stem Cells

Hira Lal Goel, Tatiana Gritsko, Bryan Pursell et al. · Cell Reports · 2014 · 111 citations · Full text

Regulation of β4-integrin expression by epigenetic modifications in the mammary gland and during the epithelial-to-mesenchymal transition

Xiaofang Yang, Bryan Pursell, Shaolei Lu et al. · Journal of Cell Science · 2009 · 110 citations · Full text

Dna Methylation, Cancer Biology, Mammary Gland Development +21